Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin.
Abstract
Background: Metastases of unknown origin (MUO) have diverse clinical presentations and, unfortunately, poor outcomes in most cases. Identifying the initial tumor location is still a considerable issue in many MUO cases. Our aim in this research was to assess the ability of F18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) to detect the site of the primary tumor before starting active treatment. Materials and methods: The study included 60 patients referred to our unit as cases of metastatic lesions with unknown primary (34 male, 26 female). PET/CT was done for all patients with its standard protocol. Results: PET/CT could suggest primary lesion in 44 cases (73.3%) with an estimated sensitivity of 97%, specificity 57%, positive predictive value 80.9%, and negative predictive value 91%. Conclusion: PET/CT is a very valuable tool in cases of MUO and is recommended as a diagnostic test for identification of the primary in cancer patients whose primary is unknown.
(2024). Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin.. SECI Oncology Journal, 12(3), 243-248.
MLA
. "Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin.", SECI Oncology Journal, 12, 3, 2024, 243-248.
HARVARD
(2024). 'Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin.', SECI Oncology Journal, 12(3), pp. 243-248.
VANCOUVER
Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin.. SECI Oncology Journal, 2024; 12(3): 243-248.